ExoVasc® PEARS

ExoVasc® Personalised External Aortic Root Support (PEARS)

ExoVasc® PEARS

The ExoVasc® PEARS is a patient-led innovation in the form of an implant that is placed around the ascending aorta. It provides support to the patient’s own aorta and aortic valve and is designed to prevent aortic dilation, dissection and rupture.

Surgical centres

The procedure for implanting the ExoVasc® PEARS is offered in over 40 centres in the UK, Europe and the rest of the world. It is not currently available for sale in the USA.

Patient stories

More than 1,100 people have had an ExoVasc® PEARS implanted. Some of them have shared their stories and experiences before and after surgery. You can read their stories here.

About Exstent

The ExoVasc® PEARS was developed by Tal Golesworthy, an engineer with Marfan syndrome, to provide an alternative to aortic root replacement surgery. 

Exstent aims to make a difference to the lives of people with aortic dilation. Our goal is to allow patients to live free from worry, without need for anticoagulant therapy and reduce the risk of requiring further surgery.

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ExoVasc® PEARS patients since 2004

Patient stories

Ray Matthews

“Anyone reading this who is thinking about or planning on having this surgery, please know that this is the surgery of the future. You get to keep all your own parts, probably won’t need to use a cardiopulmonary bypass machine, get to avoid a life of Warfarin/Coumadin, and will probably not need another follow-up surgery as so many do with the David Procedure. The recovery time is extremely fast.”
Date of procedure: 2020
Age: 40

Andrew Ellis

“I owe a great deal of thanks to Tal, Professor Pepper and their team for allowing me to be one of the initial recipients of what I am sure will become an extremely successful procedure and give many more with Marfans a better life and more positive outlook for the future.”
Date of procedure: 2008

Latest news

We regularly share news and updates that may be of interest to medical professionals, patients and prospective patients.

Nick Isiekwe’s ‘Long Road to Recovery’

Sunday Times article discussing Nick Isiekwe’s ExoVasc® PEARS surgery

Patient benefits brochures

You may find our patient benefits brochures useful when discussing the ExoVasc® PEARS with your doctor.

Regulatory information

Information on regulatory approvals for the ExoVasc® PEARS.

Find out more about the ExoVasc® PEARS